Programme

Lecturer: Dr. Artem Cherkasov (University of British Columbia, Canada)
       and Prof. Alexander Tropsha (University of North Carolina at Chapel Hill, U.S.A.)
The course site: University campus Bohunice, Kamenice 5, Brno, Czech Republic
The lectures and exercises in computer room 1.18 in A4 building

Wednesday, November 9
9:00-10:30 Lecture of Prof Tropsha: Experiment-Assisted Computational Discovery of Biological Active Compounds
10:30-11:00Break
11:00-12:30 Lecture of Dr. Cherkasov: History, Discovery and Prospectives of Modern Drugs
12:30-14:30Lunch
14:30-16:00 Practice with Dr. Cherkasov: Molecular Databases and QSAR Descriptors
16:00-16:30Break
16:30-17:30 Practice with Dr. Cherkasov: Basics of QSAR modelling
Thursday, November 10
9:00-10:30 Lecture of Dr. Cherkasov: Inductive QSAR desciptors: Background and Application for Peptide Modeling
10:30-11:00Break
11:00-12:30 Lecture of Dr. Cherkasov: Inhibition of Protein-Protein Interactions as a Novel Paradigm of Drug Discovery
12:30-14:30Lunch
14:30-16:00 Practice with Dr. Cherkasov: Ligand-based and Structure-based Drug Design
16:00-16:30Break
16:30-17:30 Practice with Dr. Cherkasov: Ligand-based and Structure-based Drug Design
Friday, November 11
9:00-10:30 Lecture of Dr. Cherkasov: Progressive Docking and Discovery of Novel Androgen Receptor Inhibitors
10:30-11:00Break
11:00-12:30 Lecture of Dr. Cherkasov: Basics of Protein Modelling and Introduction into Problem-Based Learning Class
12:30-14:30Lunch
14:30-16:00 Practice with Dr. Cherkasov: Problem-Based Learning. Case study in Drug Design, Part 1
16:00-16:30Break
16:30-17:30 Practice with Dr. Cherkasov: Problem-Based Learning. Case study in Drug Design, Part 2
Monday, November 14
9:00-10:30Exam