The group's primary interest is focused on structural and conformational studies of proteins, nucleic acids, and their complexes using high resolution NMR spectroscopy. In addition to macromolecules, also biologically interesting heterocyclic compounds and natural products are investigated by solution and solid state NMR. The experiments are complemented by theoretical calculations of NMR parameters using ab initio methodology.
In cooperation with Laboratory of Computational Chemistry and Supercomputing Centre Brno computational aspects of three-dimensional biomolecular structure determination are studied.
Figure: NMR group 2009.